Microwave Adenomyosis Treatment Malaysia, KL, Johor, Penang, Selangor
Microwave Adenomyosis Treatment Malaysia, KL, Johor, Penang, Selangor
Microwave Adenomyosis Treatment Malaysia, KL, Johor, Penang, Selangor
Microwave Adenomyosis Treatment Malaysia, KL, Johor, Penang, Selangor
Microwave ablation induces Th1-type immune response with activation of ICOS pathway in early-stage breast cancer.
Is Microwave Ablation Breast Lump treatment Expensive?
Abstract
Background Despite great advances in the treatment of breast cancer, innovative approaches are still needed to reduce metastasis. As a minimally invasive local therapy (not standard therapy for breast cancer), microwave ablation (MWA) has been attempted to treat breast cancer, but the local effect and immune response induced by MWA have seldom been reported.
Methods The clinical study was performed to determine the complete ablation rate of MWA for early-stage breast cancer. Secondary endpoints included safety and antitumor immune response. 35 subjects from this clinical study were enrolled in the current report, and the local effect was determined by pathological examinations or follow-up. To investigate MWA-induced immune response, patients treated with surgery (n=13) were enrolled as control, and blood samples were collected before and after MWA or surgery. The immune cell populations, serum cytokines, secretory immune checkpoint molecules, and T-cell receptor sequencing were analyzed.
Results Of 35 enrolled patients, 32 (91.4%) showed complete ablation. Compared with surgery, MWA induced significantly increased levels of inducible co-stimulator (ICOS)+ activated CD4+ T cells and serum interferon gamma, indicating a shift in the Th1/Th2 balance toward Th1. The activated ICOS pathway was involved in the MWA-induced adaptive immune response. T-cell receptor sequencing revealed MWA of primary tumor activated T lymphocytes expansion and recognized some cancer-specific antigens. Moreover, CD4+ effector memory T-cell response was induced by MWA, and the immune response still existed after surgical resection of the ablated tumor.
Conclusions MWA may not only be a promising local therapy but also a trigger of antitumor immunity for breast cancer, opening new avenues for the treatment of breast cancer. Combinatorial strategy using additional agents which boost MWA-induced immune response could be considered as potential treatment for clinical study for early breast cancer therapy.
Data availability statement
All data relevant to the study are included in the article or uploaded as supplementary information. All data needed to evaluate the conclusions in this paper are present in the paper and/or the supplementary information file. Additional data related to this paper may be requested from the authors.
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What is Microwave Ablation Breast Lump Treatment?
Microwave ablation (MWA) therapy has been widely used in treating liver tumors, but it has been rarely reported in spinal metastases treatment. Given the long survival period of breast cancer patients and the superficial thoracic anatomic position, treating thoracic metastases with MWA is beneficial and easy. Therefore, this study was designed to assess the feasibility and outcome of MWA performed for patients with breast cancer thoracic metastases. It aimed to assess the safety and short-term efficacy of MWA in patients with breast cancer thoracic metastases.
How Microwave Ablation Breast Lump Helps?
Breast tumor is the most commonly diagnosed tumor in women.
Percutaneous ablation is a minimally invasive method for the treatment of breast guided by using ultrasound (US) or magnetic resonance imaging (MRI), which has intrigued extensive attention as a possible first-line treatment to substitute for breast surgery procedures, such as lumpectomy.
Imaging technologies are crucial to localize the target area and to assess the treatment effect during and after ablation treatment. US is most valuable in providing the location of the electrode within the lesion and in real-time monitoring the ablation.
In recent years, several ablation techniques, including radiofrequency ablation (RFA), laser ablation, cryoablation and microwave ablation (MWA) have been evaluated in clinical trials .
Compared with others ablation techniques, MWA is a promising technique because it can preferentially heat and damage high-water-content breast tumors, whereas the lesser degrees of heating lower-water-content fatty and glandular tissues.
Microwave ablation was a safe and efficient method in the treatment of the benign breast tumors.
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Best Microwave Ablation Breast Lump Treatment In Kuala Lumpur, Selangor, Pennang Malaysia!
Microwave ablation (MWA) is a minimally-invasive treatment for cancer. MWA uses ultrasound, computed tomography (CT), or magnetic resonance imaging (MRI) to guide placement of a needle-like probe into a tumor. MWA uses microwaves to heat and destroy the tumor. Doctors use MWA for the same indications as RFA.
WSM MEDIC provides best Microwave Ablation Breast Lump Treatment in Malaysia.
Microwave Ablation Breast Lump Treatment in Malaysia.
Laser ablation therapy is a less invasive alternative to traditional breast cancer operations like lumpectomies. Rather than surgically removing the tumor and a small amount of surrounding tissue, this procedure uses targeted lasers to precisely destroy small tumors.
No worries, both are non-cancerous uterine growths!
What Are Fibroids & Adenomyosis?
Uterine fibroids, also known as leiomyomas (lie-o-my-O-muhs) or myomas are non-cancerous uterine growths that commonly appear in your uterus (medical term for your womb) during childbearing age. They are not correlated to an elevated risk of uterine cancer and almost never turn cancerous.
Adenomyosis happens when the tissue that typically lines the uterus develops into the muscular wall of the uterus, resulting in a disease condition called adenomyosis (ad-uh-no-my-O-sis). During each menstrual cycle, the misplaced tissue will continually thicken, degrades, and bleeds. Eventually, the uterus expand and resulting in painful, heavy periods.
Why should women know about fibroids?
By the age of 50, about 20% to 80% of women have fibroids. Women in their 40s and early 50s are most likely to get fibroids. Symptoms aren’t always present in women with fibroids. Fibroids can be difficult to live with for those who do have symptoms. Some people experience pain and heavy menstrual bleeding. Fibroids can also put pressure on the bladder, causing frequent urination, or on the rectum, resulting in rectal pressure. Fibroids can cause the abdomen (stomach area) to expand, making a woman appear pregnant.
Fibroids can cause such heavy bleeding that you may be at risk for developing anemia. When a fibroid blocks a fallopian tube or interferes with your reproductive cycle in any way, it might make it difficult to get pregnant.
Who Gets Fibroids?
Are you experiencing? one of the above?
Don’t worry! The minimally invasive Microwave Ablation for Uterine Fibroids and Adenomyosis can help!
The Latest Uterus Conserving Treatment
Microwave Ablation (MWA)
- Without Cutting & Removing Any Tissue
- Go Home The Same Day
- Fast Return To Normal Daily Activities
First time hearing of this technology?
The same Microwave Ablation Technology has been available in Malaysia since year 2012, widely used by Interventional Radiologists to treat solid cancerous tumours in liver, lung, kidney, adrenal, spleen, bone and others as a Minimally Invasive Cancer Therapy.
How does Microwave Ablation work?
MWA uses electromagnetic waves to produce a tissue heating effect. The oscillation of polar molecules produces frictional heating, ultimately generating tissue coagulation necrosis within the tumour. It destroys and eradicates non-cancerous lesions / adenomyosis by ablating them with thermal ablation.
Mechanism of Microwave Thermal Ablation generates a series of biochemical changes, such as tumour cell dehydration, intracellular protein denaturation, and coagulation that brings the synthesis of tumour cell’s deoxyribonucleic acid (DNA) and protein to a halt. It also destroys the blood supply of the lesion, which results in the necrosis of tumour cells. The treated tumour will be absorbed by body over time, no tissue removal is required.
The Microwave Ablation Procedure
Microwave Ablation treats uterine fibroids and adenomyosis without cutting and removing the uterus. Treatment can be performed by abdominal, vaginal or laparoscopic approach.
MWA Abdominal Approach
Under real-time ultrasound image guidance, a 1.6mm MWA antenna will be precisely inserted into the targeted area (fibroid).
Microwave heat energy is generated uniformly to kill the tissue inside the fibroid. A 10cm fibroid in diameter can be treated completely in 15 minutes. The treated fibroid will become necrosis, shrink & absorbed by our body over time.
No open wound, no stitch, no scar. Maximum preservation of uterus structure and function.
Why Microwave Ablation?
Precise & Safe
The whole procedure will be precisely monitored by real-time ultrasound imaging to clearly locate the fibroid/adenomyosis and monitor the needle placement as well the ablation progress.
Preserve Your Womb
MWA offers a no-cut, no removal of uterus treatment option for fibroids and adenomyosis. Beneficial for women who have strong desire to preserve their uterus.
Minimally Invasive
- Only a tiny antenna/needle (1.6mm) is inserted into the targeted fibroid
- Excellent cosmetic outcome, no ugly scar
- Almost painless
- Retain uterus structure and function
Fast Treatment Time
- MWA Treatment generally take about 15 minutes for fibroids size of 10cm
- Go home on the same day or next day
- Significant relief of symptoms
- Quick recovery to normal daily activities
In conclusion,
MWA is a minimally-invasive treatment, with benefits as follows:
Almost painless, without cutting or stitching, keeping the uterus intact
Tiny incision, no scarring
Precise treatment, under real-time ultrasound guidance
Go home on the same day or next day
Fast treatment time
Quick recovery
Local Anaesthesia (LA) is possible
